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Laser device may end pin pricks, improve quality of life for diabetics

August 21st, 2014
A new system developed by Princeton researchers uses a laser to allow diabetics to check their blood sugar without pricking their skin. Members of the research team included, from left, Sabbir Liakat, a graduate student in electrical engineering; Claire Gmachl, the Eugene Higgins Professor of Electrical Engineering; and Kevin Bors, who graduated in 2013 with a degree in electrical engineering. (Photos by Frank Wojciechowski)

Princeton University researchers have developed a way to use a laser to measure people's blood sugar, and, with more work to shrink the laser system to a portable size, the technique could allow diabetics to check their condition without pricking themselves to draw blood.

"We are working hard to turn engineering solutions into useful tools for people to use in their daily lives," said Claire Gmachl, the Eugene Higgins Professor of Electrical Engineering and the project's senior researcher. "With this work we hope to improve the lives of many diabetes sufferers who depend on frequent blood glucose monitoring."

In an article published June 23 in the journal Biomedical Optics Express, the researchers describe how they measured blood sugar by directing their specialized laser at a person's palm. The laser passes through the skin cells, without causing damage, and is partially absorbed by the sugar molecules in the patient's body. The researchers use the amount of absorption to measure the level of blood sugar.

Sabbir Liakat, the paper's lead author, said the team was pleasantly surprised at the accuracy of the method. Glucose monitors are required to produce a blood-sugar reading within 20 percent of the patient's actual level; even an early version of the system met that standard. The current version is 84 percent accurate, Liakat said.

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Besides Liakat and Gmachl, researchers included Kevin Bors, Class of 2013, Laura Xu, Class of 2015, and Callie Woods, Class of 2014, who worked on the project as undergraduate students majoring in electrical engineering; and Jessica Doyle, a teacher at Hunterdon Regional Central High School.

Read the full story (link is external) here.

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